Painful neuropathy: altered central processing maintained dynamically by peripheral input
RH Gracely, SA Lynch, GJ Bennett - Pain, 1992 - Elsevier
We performed sensory assessments before and during diagnostic tourniquet-cuff and local
anesthetic blocks in 4 patients diagnosed with reflex sympathetic dystrophy (RSD). All
patients complained of mechano-allodynia; lightly touching the skin evoked an intense pain
sensation. At detection levels, electrical stimuli were perceived as painful, suggesting that
the mechano-allodynia was mediated by Aβ low-threshold mechanoreceptor afferents. Aβ-
mediated allodynia was further supported by reaction time latencies to painful electrical …
anesthetic blocks in 4 patients diagnosed with reflex sympathetic dystrophy (RSD). All
patients complained of mechano-allodynia; lightly touching the skin evoked an intense pain
sensation. At detection levels, electrical stimuli were perceived as painful, suggesting that
the mechano-allodynia was mediated by Aβ low-threshold mechanoreceptor afferents. Aβ-
mediated allodynia was further supported by reaction time latencies to painful electrical …
